癌变·畸变·突变 ›› 2006, Vol. 18 ›› Issue (5): 390-391.doi: 10.3969/j.issn.1004-616x.2006.05.016

• 论著 • 上一篇    下一篇

雪蛙油软胶囊抗氧化作用的研究

尤秀新/毛焕新   

  1. 吉林省卫生厅卫生监督所,吉林 长春 130062
  • 收稿日期:2006-03-22 修回日期:2006-04-28 出版日期:2006-09-30 发布日期:2006-09-30
  • 通讯作者: 尤秀新

The Antioxidant Effects of the Snow Frog Oil Soft Capsule

YOU Xiu-xin,MAO Huan-xin   

  1. Institute of Public Health Surveillance of Jilin Provincial Health Bureau, Changchun 130062,Jilin,China
  • Received:2006-03-22 Revised:2006-04-28 Online:2006-09-30 Published:2006-09-30
  • Contact: YOU Xiu-xin

摘要: 背景与目的: 探讨雪蛙油软胶囊的抗氧化作用。 材料与方法:分2.5、0.5和0.1 g/kg 3个雪蛙油剂量实验组,给予Wistar雌性大鼠雪蛙油灌胃,同时设溶剂对照组(食用色拉油)。连续给予受试物8周后,测定血清超氧化物岐化酶(Superoxide dismutase,SOD)、谷胱甘肽过氧化物酶(Glutathione peroxidase,GSH-Px)和肝脏的丙二醛(Malondiadehycle,MDA)。 结果: 雪蛙油软胶囊有升高血清SOD和GSH_Px值和降低肝脏MDA值的作用。 结论: 雪蛙油软胶囊具有明显抗氧化作用。

关键词: 雪蛙油软胶囊, 血清SOD, 血清GSH-Px, 肝脏MDA, 抗氧化

Abstract: BACKGROUND & AIM: To explore the antioxidant effects of snow frog oil capsule. MATERIAL AND METHODS: The mice were divided into four groups,study groups were given snow frog oil at a dose of 2.5,0.5,0.1 g/kg,while distilled water was given in control group.The levels of SOD and GSH_Px in serum and the level of MDA in the liver tissue were evaluated. RESULTS: Snow frog oil capsule could increase the levels of SOD and GSH-Px in serum and decrease the level of MDA in liver tissue. CONCLUSION: Snow frog oil capsule antioxidant effects.

Key words: capsule of snowfrog oil, SOD in serum, GSH-Px in serum, MDA in the liver tissue, antioxidant effects